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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 20 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IGF-I Rabbit Polyclonal Antibody detects endogenous levels of IGF-I protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IGF-I(Insulin-like growth factor I) also known as IGF1 is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. IGF-I plays a vital role in growth and development, acting in both autocrine and paracrine manners to stimulate vascular smooth muscle cell proliferation. IGF-I is primarily located in the bloodstream and produced mainly by the liver in response to growth hormone stimulation. This localization allows IGF-I to exert systemic effects on tissues throughout the body, influencing processes such as cell growth, differentiation, and metabolism. IGF-I is essential for normal bone growth and repair, as well as for regulation of renal function and immune response. IGF-I biological activity is modulated by a family of six IGF-binding proteins (IGFBP1-6), which can either enhance or inhibit actions, thereby fine-tuning effects on various physiological processes.
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| Product Image Gallery | |
 Western blot analysis of extracts on SW480, HT29 cells, using IGF-I Rabbit Polyclonal Antibody (EAB14173) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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