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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 20 | Human, Mouse, Rat, Pig |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IGF-II Rabbit Polyclonal Antibody detects endogenous levels of IGF-II protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IGF-II also known as IGF2 is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. IGF-II plays a crucial role in fetal development, acting as a growth factor primarily expressed in the placenta and regulated by placental lactogen. IGF-II is essential for proper growth and development during prenatal stages, influencing cell proliferation and differentiation. IGF-II is involved in the regulation of metabolic processes and has been linked to various gene variants associated with overfeeding-induced metabolic changes. The human IGF-II gene is located on chromosome 11p15.5 and encodes a 180 amino acid precursor protein that undergoes post-translational modifications, including glycosylation, which are vital for stability and biological activity. |
| Product Image Gallery | |
 Western blot analysis of extracts on HCT116 cells, using IGF-II Rabbit Polyclonal Antibody (EAB14174) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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