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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, FC, ELISA | 17 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 FC=1:20-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-4 Rabbit Polyclonal Antibody detects endogenous levels of IL-4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-4(Interleukin-4) also known as BCGF1, BSF is a pleiotropic cytokine produced by activated T cells. IL-4 plays a crucial role in the immune system by promoting the growth and differentiation of immune cells, particularly by enhancing the Th2 cell lineage while suppressing Th1 responses. IL-4′s importance extends to inducing immunoglobulin class switching, which is vital for effective immune responses. Specifically, IL-4 stimulates B cells to produce immunoglobulin E (IgE) and enhances the secretion of immunoglobulin G4 (IgG4), while simultaneously inhibiting the production of other immunoglobulin classes such as IgM, IgA, IgG1, IgG2, and IgG3. The regulation of these immunoglobulin classes is essential for maintaining a balanced immune response and preventing allergic reactions. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using IL-4 Rabbit Polyclonal Antibody (EAB11626) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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