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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 20 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-7 Rabbit Polyclonal Antibody detects endogenous levels of IL-7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-7(Interleukin-7) is a cytokine important for B and T cell development. IL-7 plays a crucial role in the immune system, primarily by promoting the survival and proliferation of lymphocytes, particularly T cells and B cells. IL-7 is located in the extracellular space and is secreted by stromal cells in the bone marrow and thymus, where IL-7 binds to IL-7 receptor on target cells. This interaction is vital for lymphocyte development and homeostasis, as IL-7 not only supports the survival of immune cells but also influences differentiation and function. IL-7 receptor is a heterodimer composed of an IL-7 receptor-specific chain and the common gamma chain, which is shared with other interleukin receptors. Dysregulation of IL-7 signaling has been implicated in various immunological disorders, including autoimmune diseases and lymphoid malignancies, making IL-7 a significant target for therapeutic interventions. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, Human kidney cells, using IL-7 Rabbit Polyclonal Antibody (EAB14193) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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