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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 142 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-16 Rabbit Polyclonal Antibody detects endogenous levels of IL-16 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-16(Interleukin 16) is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. IL-16 plays a crucial role in the immune response as a cytokine with chemoattractant properties specifically for CD4+ T lymphocytes. IL-16 is secreted by activated eosinophils during allergic reactions, contributing to the recruitment of immune cells to sites of inflammation. IL-16 interaction with CD4 receptor triggers a signaling cascade that activates protein kinase C (PKC) pathways, leading to various physiological changes in target cells. Understanding IL-16 function is vital, as IL-16 not only mediates the inflammatory response but also helps elucidate the underlying mechanisms of allergic diseases, making IL-16 a significant target for therapeutic interventions. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, Raji, HepG2, Mouse brain cells, using IL-16 Rabbit Polyclonal Antibody (EAB14198) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tissue, using IL-16 Rabbit Polyclonal Antibody (EAB14198) at 1:100 dilution.
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