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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 31 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-33 Rabbit Polyclonal Antibody detects endogenous levels of IL-33 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-33(Interleukin-33) is a cytokine that binds to the IL1RL1/ST2 receptor. IL-33 plays a crucial role in the immune response, acting as an alarmin that signals tissue damage and promotes inflammation. IL-33 is primarily expressed in epithelial cells and is released upon cellular stress or injury, which is vital for initiating protective immune responses. IL-33 in the extracellular space can activate various immune cells, including T helper 2 cells, mast cells, and eosinophils, thereby influencing the development of allergic and autoimmune diseases. Understanding IL-33 function is essential for developing therapeutic strategies targeting inflammatory conditions, as IL-33 dysregulation is implicated in diseases such as asthma, rheumatoid arthritis, and inflammatory bowel disease. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using IL-33 Rabbit Polyclonal Antibody (EAB14204) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsilla tissue, using IL-33 Rabbit Polyclonal Antibody (EAB14204) at 1:100 dilution.
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