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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 14 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KCNE1 Rabbit Polyclonal Antibody detects endogenous levels of KCNE1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
KCNE1 is a member of the potassium channel KCNE family. KCNE1 protein plays a crucial role in regulating voltage-gated potassium channels, particularly in forming I_Kr channel, which is essential for cardiac repolarization. KCNE1 protein interacts with HERG channel, a key component of cardiac action potential, and proper function is vital for maintaining normal heart rhythm. Mutations in KCNE1 gene can lead to severe cardiac conditions, including congenital long QT syndrome, highlighting KCNE1′s importance in both cardiac health and disease. KCNE1 gene is located on chromosome 21, and expression is tightly regulated in various tissues, ensuring potassium ion flow is appropriately modulated during cellular excitability. |
| Product Image Gallery | |
 Western blot analysis of extracts on HCT116 cells, using KCNE1 Rabbit Polyclonal Antibody (EAB14220) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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