www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 116 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KL/Klotho Rabbit Polyclonal Antibody detects endogenous levels of KL/Klotho protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Klotho also known as KL, HFTC3 is a type-I membrane protein that is related to beta-glucosidases. The amino terminal extracellular domain has two internal repeats, known as KL-1 and KL-2, which have partial sequence homology to beta-glucosidases and lactase glycosylceramidase, suggesting a role for Klotho in sphingolipid metabolism. The human klotho gene maps to chromosome 13q12 and encodes a 1012 amino acid protein that is abundant in the kidney and brain. Chronic renal failure (CRF) patients express lower levels of klotho mRNA and protein in the kidneys. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse kidney, Mouse brain cells, using KL/Klotho Rabbit Polyclonal Antibody (EAB14225) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
