www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 55 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KLF4 Rabbit Polyclonal Antibody detects endogenous levels of KLF4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
KLF4 also known as GKLF is a protein that belongs to the Kruppel family of transcription factors. a group of transcription factors characterized by zinc finger domains, which are critical for binding DNA. The zinc finger structure consists of repeated motifs that interact specifically with DNA sequences, allowing KLF4 to regulate gene expression involved in cellular processes such as proliferation, differentiation, and stress response. This structural feature maintains epithelial integrity and regulates cell cycle arrest, particularly in tissues like the gastrointestinal tract and skin. KLF4′s ability to modulate gene expression through zinc finger domains makes KLF4 a key player in development and cellular homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, BT474, 293T, A431, Mouse brain cells, using KLF4 Rabbit Polyclonal Antibody (EAB14226) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
