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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 22 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LCN2/NGAL Rabbit Polyclonal Antibody detects endogenous levels of LCN2/NGAL protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LCN2 also known as NGAL is a protein that belongs to the lipocalin family. LCN2 plays a crucial role in immune response, particularly in inflammation. LCN2 is primarily located in the extracellular space and is secreted by activated neutrophils and epithelial cells, especially during inflammatory conditions. LCN2 presence in the extracellular environment allows interaction with various ligands, including bacterial products, which can modulate immune responses and promote tissue repair. LCN2 has been implicated in iron homeostasis regulation and has shown binding to iron, suggesting a protective role against oxidative stress. LCN2′s ability to act as a scavenger for bacterial products highlights importance in anti-inflammatory processes, making LCN2 a valuable target for research in inflammatory and neoplastic diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29, Mouse spleen cells, using LCN2/NGAL Rabbit Polyclonal Antibody (EAB14237) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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