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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 132 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Leptin Receptor/Ob-R Rabbit Polyclonal Antibody detects endogenous levels of Leptin Receptor/Ob-R protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Leptin Receptor also known Ob-R, LEPR is a member of the class I cytokine receptor family and structurally resembles the gp130 signal-transducing component of the IL-6 receptor complex. Leptin Receptor plays a critical role in regulating body weight, energy balance, and neuroendocrine functions by mediating the effects of leptin, a hormone produced by adipose tissue that suppresses appetite and promotes energy expenditure. Predominantly expressed in the hypothalamus and choroid plexus, Leptin Receptor is pivotal in signaling pathways that control food intake and body weight homeostasis. Dysregulation or mutations in the leptin receptor can lead to obesity and metabolic disorders, including type II diabetes, making Leptin Receptor a significant target for research in metabolic regulation and energy homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562, MCF7 cells, using Leptin Receptor/Ob-R Rabbit Polyclonal Antibody (EAB14292) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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