LIF Rabbit Polyclonal Antibody
Catalog #:EAB14239
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 22 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity LIF Rabbit Polyclonal Antibody detects endogenous levels of LIF protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P15018

Entrez Gene ID

3976

Product Description

LIF(eukemia inhibitory factor) is a pleiotropic cytokine with roles in several different systems. LIF plays a crucial role in maintaining the pluripotency of embryonic stem (ES) cells by inhibiting their spontaneous differentiation, which is vital for stem cell research and potential therapeutic applications. This 202 amino acid secreted glycoprotein is produced by various cell types, including activated T lymphocytes, monocytes, mast cells, and neuronal cells, and is essential for promoting the survival and growth of axons in vitro. Additionally, LIF is implicated in immune tolerance at the maternal-fetal interface, suggesting its importance in reproductive biology. Beyond its role in stem cell maintenance, LIF may also influence fat and bone metabolism and is involved in the regulation of epithelial conversion during kidney development.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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