| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LOX Rabbit Polyclonal Antibody detects endogenous levels of LOX protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LOX(Lysyl oxidase) also known as AAT10 is a member of the lysyl oxidase family of proteins. LOX plays a critical role in the extracellular matrix by catalyzing the oxidative deamination of peptidyl lysine residues in collagens and elastin, leading to the formation of cross-links that provide structural integrity to tissues. This function is particularly important as LOX contributes to the mechanical properties of connective tissues, influencing their strength and elasticity. Dysregulation of LOX activity can result in pathological conditions, such as fibrosis, where excessive cross-linking leads to tissue stiffness and impaired function. LOX is essential for normal cardiovascular and respiratory system development, and LOX expression is intricately linked to processes such as wound healing, cell motility, and differentiation. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, A431 cells, using LOX Rabbit Polyclonal Antibody (EAB14269) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. A431
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