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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 38 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Lumican Rabbit Polyclonal Antibody detects endogenous levels of Lumican protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Lumican also known as LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. Lumican plays a crucial role in regulating collagen fibrillogenesis, which is essential for maintaining structural integrity of tissues. Lumican is predominantly found in corneal stroma and interstitial matrices of various tissues, including heart, aorta, skeletal muscle, skin, and intervertebral discs. Lumican′s ability to modulate collagen assembly into higher-order fibrils is vital for controlling diameter of these fibrils, thereby influencing tissue strength and elasticity. Notably, Lumican is present in extracellular matrix of human articular cartilage throughout life, with significantly higher levels observed in adults, indicating importance in cartilage health and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on PC12 cells, using Lumican Rabbit Polyclonal Antibody (EAB14246) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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