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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 43 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GDF8/MSTN Rabbit Polyclonal Antibody detects endogenous levels of GDF8/MSTN protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GDF8(Growth differentiation factor 8) also known as Myostatin, MSTN is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. GDF8 plays a crucial role in regulating skeletal muscle growth by inhibiting myoblast proliferation and differentiation, making GDF8 a significant factor in muscle development and homeostasis. This negative regulatory function is particularly important in the context of muscle wasting conditions, where elevated levels of GDF8 can contribute to muscle atrophy. Understanding GDF8 mechanisms is vital for developing therapeutic strategies aimed at combating muscle degenerative diseases and enhancing muscle regeneration. |
| Product Image Gallery | |
 Western blot analysis of extracts on BT474, Mouse heart, Mouse liver cells, using GDF8/MSTN Rabbit Polyclonal Antibody (EAB14283) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using GDF8/MSTN Rabbit Polyclonal Antibody (EAB14283) at 1:100 dilution.
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