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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 223 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MYH6 Rabbit Polyclonal Antibody detects endogenous levels of MYH6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cardiac myosin heavy chain is a critical component of the sarcomeric thick filaments in heart muscle fibers, playing a central role in muscle contraction by interacting with actin filaments to generate force. There are two main isoforms in the heart, MYH6 (alpha-myosin heavy chain) and MYH7 (beta-myosin heavy chain), which are differentially expressed and contribute to cardiac performance. Post-translational modifications of the myosin heavy chain, such as phosphorylation, glycation, and oxidative modifications, can alter cardiac muscle contractility and responsiveness to physiological stimuli. ysregulation of these modifications has been implicated in cardiac diseases such as cardiomyopathies and heart failure. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse heart cells, using MYH6 Rabbit Polyclonal Antibody (EAB14289) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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