www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 86 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NOX5 Rabbit Polyclonal Antibody detects endogenous levels of NOX5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NOX5 (NADPH oxidase 5) is a member of the NADPH oxidase family. NOX5 plays a crucial role in generating reactive oxygen species, particularly superoxide, which is essential for various cellular processes, including signaling pathways that regulate cell proliferation and apoptosis. Notably, NOX5 is unique among its family due to its N-terminal region, which contains three EF-hand motifs that bind calcium ions, allowing NOX5 to respond to intracellular calcium fluctuations. This calcium sensitivity is vital for Nox5 function, as calcium binding enables direct activation in response to physiological stimuli, thereby influencing processes such as immune response and vascular function. NOX5 expression in lymphoid organs and testis highlights its importance in both immune system regulation and reproductive biology, making NOX5 a significant target for research in these areas. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using NOX5 Rabbit Polyclonal Antibody (EAB14313) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
