www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 16 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NPPA Rabbit Polyclonal Antibody detects endogenous levels of NPPA protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NPPA also known as ANP, ANF belongs to the natriuretic peptide family. NPPA plays a crucial role in regulating blood pressure and fluid balance within the body, primarily by promoting natriuresis, which is the excretion of sodium through urine. This function is vital for maintaining electrolyte homeostasis and preventing conditions such as hypertension and heart failure. NPPA is secreted by cardiac atrial cells in response to increased blood volume and pressure, acting as a counter-regulatory mechanism to the renin-angiotensin-aldosterone system. NPPA′s structure features a unique 17-residue ring formed by an intramolecular disulfide bond, which is essential for biological activity and receptor binding. |
| Product Image Gallery | |
 Western blot analysis of extracts on U2OS cells, using NPPA Rabbit Polyclonal Antibody (EAB14316) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
