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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 228 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PCM1 Rabbit Polyclonal Antibody detects endogenous levels of PCM1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PCM1(Pericentriolar material 1) is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. PCM1 associates securely with the centrosome complex through G1, S, and part of G2. Late in G2, as cells prepare for mitosis, PCM1 dissociates from the centrosome and remains evenly diffused throughout the cell during mitosis before re-associating with centrosomes in G1 phase progeny cells. PCM1′s chromosomal location on 8p22-p21.3 draws interest since this region commonly shows deletions in several tumors. In thyroid tumor tissue, PCM1 expression significantly decreases with altered subcellular localization. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raji cells, using PCM1 Rabbit Polyclonal Antibody (EAB14351) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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