www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 53 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PAX3 Rabbit Polyclonal Antibody detects endogenous levels of PAX3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PAX3(Paired box 3) is a member of the paired box (PAX) family of transcription factors. PAX3 plays a significant role in early neurogenesis, particularly in the development of the central nervous system. Pax-3 contains both a paired domain and a paired-type homeodomain, which are essential for DNA-binding capabilities, allowing regulation of target genes involved in cell differentiation and proliferation. Pax-3 expression is primarily localized to mitotic cells in the ventricular zone of the developing spinal cord, as well as in specific regions of the hindbrain, midbrain, and diencephalon. During embryonic development, Pax-3 is also expressed in neural crest cells, which are critical for the formation of various structures, including the craniofacial mesectoderm and limb mesenchyme. |
| Product Image Gallery | |
 Western blot analysis of extracts K562 cells, using PAX3 Rabbit Polyclonal Antibody (EAB14367) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
