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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | IHC-P, IF/ICC, ELISA | 97 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DDR2 Rabbit Polyclonal Antibody detects endogenous levels of DDR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DDR2 also known as TKT, TYRO10 is a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. DDR2 plays a crucial role in mediating cellular responses to collagen, which is vital for tissue remodeling and repair. Located primarily on the cell surface, DDR2 interacts with collagen fibers, triggering signaling pathways that influence cell adhesion, migration, and differentiation. This interaction is particularly important in wound healing and fibrosis, as DDR2 activation leads to upregulation of matrix metalloproteinase-1, an enzyme that degrades extracellular matrix components. |
| Product Image Gallery | |
 Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue, using DDR2 Rabbit Polyclonal Antibody (EAB11975) at 1:200 dilution.
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