| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC | 74 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACOX1 Rabbit Polyclonal Antibody detects endogenous levels of ACOX1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACOX1(Acyl-coenzyme A oxidase 1) is a crucial 660 amino acid protein localized in the peroxisome, where ACOX1 plays a vital role in lipid metabolism. Specifically, ACOX1 catalyzes the desaturation of very long chain acyl-CoA substrates into 2-trans-enoyl-CoA, a reaction that is essential for the breakdown of fatty acids and involves the use of FAD as a cofactor. This enzymatic activity not only facilitates energy production but also contributes to the regulation of cellular lipid levels, which is critical for maintaining cellular homeostasis. Defects in ACOX1 can lead to pseudoneonatal adrenoleukodystrophy (pseudo-NALD), a serious condition characterized by neurological impairments and metabolic dysfunctions, underscoring ACOX1′s significance in human health. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse liver, Mouse kidney cells, using ACOX1 Rabbit Polyclonal Antibody (EAB14394) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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