www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC | 37 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IF/ICC=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TRAP Rabbit Polyclonal Antibody detects endogenous levels of TRAP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRAP(Tartrate resistant acid phosphatase) also known as ACP5 is an iron-containing glycoprotein that plays a crucial role in bone metabolism by catalyzing the hydrolysis of phosphate esters, TRAP is essential for bone resorption and remodeling. TRAP is primarily located in osteoclasts, the cells responsible for bone degradation, and TRAP activity is vital for maintaining bone homeostasis. TRAP regulation is particularly important in pathological conditions such as osteoporosis and certain cancers, where osteoclast activity is dysregulated. Additionally, receptor activator of NFkB ligand (RANKL) activates TRAP, which enhances osteoclast differentiation and function, further underscoring TRAP significance in bone health and disease. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using TRAP Rabbit Polyclonal Antibody (EAB14396) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
