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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P | 28 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | 14-3-3 eta Mouse Monoclonal Antibody detects endogenous levels of 14-3-3 eta protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
14-3-3 eta is a member of the 14-3-3 protein family, which plays a crucial role in cellular signaling pathways, particularly in regulating apoptosis, mitogenic signaling, and cell-cycle checkpoints, making 14-3-3 eta protein significant in cancer biology. 14-3-3 eta protein is primarily located in the cytoplasm and nucleus, where 14-3-3 eta protein interacts with various target proteins to modulate their activity. 14-3-3 eta protein′s ability to sequester proteins in the cytoplasm or facilitate their nuclear import/export is vital for maintaining cellular homeostasis and responding to stress signals. 14-3-3 eta protein′s interaction with ligands, which often contain a specific 14-3-3 consensus binding motif, is essential for regulating numerous cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Rat brain cells, using 14-3-3 eta Mouse Monoclonal Antibody (EAB13301) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue, using 14-3-3 eta Mouse Monoclonal Antibody (EAB13301) at 1:200 dilution.
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