| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 24 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cox2/MTCO2 Rabbit Polyclonal Antibody detects endogenous levels of Cox2/MTCO2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytochrome c oxidase subunit II (COX2), also known as MTCO2, COII is a crucial component of the oxidative phosphorylation complex IV, which plays a vital role in cellular respiration. Located in the mitochondrial inner membrane, Cox2 is one of three subunits encoded by mitochondrial DNA that form the catalytic core of respiratory complex IV, alongside Cox1 and Cox3. This enzyme complex is responsible for the reduction of molecular oxygen to water, a process that releases energy used to pump protons across the mitochondrial inner membrane, creating an electrochemical gradient essential for ATP synthesis. Proper functioning of Cox2 is critical, as defects can lead to impaired energy production and are associated with various pathologies, including tumor formation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, CasKi cells, using Cox2/MTCO2 Rabbit Polyclonal Antibody (EAB14349) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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