| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 34 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CDX2 (Ser283) Rabbit Polyclonal Antibody detects endogenous levels of CDX2 protein only when phosphorylated at Ser283. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CDX2 is a member of the caudal-related homeobox transcription factor gene family. CDX2 plays a significant role in the development and differentiation of the intestinal epithelium. Cdx2 is primarily expressed in the small intestine and colon, where Cdx2 regulates the expression of genes involved in maintaining the intestinal phenotype and promoting cellular growth. The proper functioning of Cdx2 is vital for the anterior-posterior patterning of the intestinal epithelium, as Cdx2 influences the proliferation and differentiation of cells along the crypt-villus axis. Notably, a decrease in Cdx2 expression has been linked to colorectal tumorigenesis, highlighting Cdx2′s importance in tumor suppression. |
