www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF | 25 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 IF=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GAP43 Mouse Monoclonal Antibody detects endogenous levels of GAP43 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GAP43(growth associated protein 43) also known as B-50, PP46 is a crucial component for regenerative response in the nervous system. GAP43 plays a vital role in neuronal development and regeneration, being predominantly expressed in growth cones during these processes. GAP43 presence is crucial for axonal outgrowth and synapse formation, which are essential for proper neuronal communication and repair following injury. GAP43 localization in the axonal membrane underscores GAP43′s importance in facilitating dynamic changes required for neuronal plasticity and regeneration. Additionally, GAP43 interacts with specific proteins, such as the neuron-specific Elav/Hu family member HuD, which stabilizes GAP43 mRNA, thereby enhancing protein levels during neuronal development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T, Mouse brain, Rat brain cells, using GAP43 Mouse Monoclonal Antibody (EAB11587) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 25 kDa; Observed band size: 38,43 kDa  Immunohistochemical analysis of paraffin-embedded Rat brain tissue, using GAP43 Mouse Monoclonal Antibody (EAB11587) at 1:500 dilution.
|
