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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 25 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MOB1A Rabbit Polyclonal Antibody detects endogenous levels of MOB1A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MOB1A is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. MOB1A protein plays a crucial role in cell cycle regulation and tumor suppression, functioning as a key component of the Hippo signaling pathway, which is essential for controlling cell growth and preventing excessive cell proliferation. This pathway is particularly important in maintaining tissue homeostasis and preventing cancer development, as MOB1A regulates the activity of downstream effectors like NDR-family protein kinases and LATS1 kinase. Through binding and modulating these kinases, MOB1A helps orchestrate cellular responses to various stimuli, including stress and growth factors, thereby influencing cell fate decisions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, K562, HMC1 cells, using MOB1A Rabbit Polyclonal Antibody (EAB13430) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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