IFITM2 Rabbit Polyclonal Antibody
Catalog #:EAB11022
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 15 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000
Product Information
Conjugate Unconjugate
Specificity IFITM2 Rabbit Polyclonal Antibody detects endogenous levels of IFITM2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q01629

Entrez Gene ID

10581

Product Description

IFITM2(Interferon induced transmembrane protein 2) is an interferon-stimulated gene encoding a small membrane-associated protein that contributes to intrinsic innate immunity. IFITM2 localizes primarily to endosomal and lysosomal membranes, where it can alter membrane properties to restrict entry and trafficking of enveloped viruses, integrating with type I/II interferon signaling and broader antiviral restriction factor networks. Its activity is linked to regulation of endocytic pathways, vesicular acidification, and membrane fusion events, processes that also intersect with inflammatory signaling and cellular stress responses. Dysregulated IFITM2 expression has been associated with altered susceptibility to viral infection and immune-related phenotypes, making it relevant for studies of host–pathogen interactions and interferon-driven cellular programs.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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