| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 29 | Human, Mouse, Rat, Monkey, Dog |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AQP2 Rabbit Polyclonal Antibody detects endogenous levels of AQP2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AQP2(Aquaporin 2) is a water channel protein located in the kidney collecting tubule, It belongs to the MIP/aquaporin family. AQP2 plays a crucial role in regulating water balance in the body, specifically by facilitating water reabsorption in the kidney collecting ducts in response to vasopressin. This function is vital for maintaining homeostasis, particularly in conditions of dehydration or increased plasma osmolality. AQP2 is unique among aquaporins as the only water channel directly regulated by vasopressin, which enhances activity and promotes urine concentration. Proper functioning of AQP2 is essential for preventing conditions such as diabetes insipidus, where the body fails to concentrate urine, leading to excessive urination and thirst. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7, Rat kidney cells, using AQP2 Rabbit Polyclonal Antibody (EAB11036) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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