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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 39 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CK1 alpha (Thr321) Rabbit Polyclonal Antibody detects endogenous levels of CK1 alpha protein when phosphorylated at Thr321. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CK1 alpha also known as Casein Kinase I alpha, CK1, CSNK1A1 is a member of the protein kinase superfamily. CK1 alpha plays a crucial role in several cellular processes, including the regulation of the Wnt signaling pathway, which is vital for cell proliferation and differentiation. CK1 alpha is primarily located in the cytoplasm, where CK1 alpha is involved in the phosphorylation of various substrates, thereby influencing key signaling pathways that govern cellular functions such as DNA repair, circadian rhythms, and apoptosis. CK1 alpha′s ability to modulate these pathways underscores CK1 alpha′s importance in maintaining cellular homeostasis and potential implications in various diseases, including cancer and neurodegenerative disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc cells, using Phospho-CK1 alpha (Thr321) Rabbit Polyclonal Antibody (EAB11047) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 39 kDa; Observed band size: 35 kDa |
