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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 67 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CTPS1 Rabbit Polyclonal Antibody detects endogenous levels of CTPS1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CTPS1(CTP synthase 1) also known as GATD5, CTPS is an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). CTPS1 is primarily located in the cytoplasm, where CTPS1 facilitates the availability of CTP, a critical building block for RNA synthesis and cellular energy metabolism. CTPS1 regulation is complex, involving various post-translational modifications, including phosphorylation by protein kinase C, which can modulate CTPS1 activity and influence cellular responses to growth signals. Notably, the gene encoding CTPS1 is situated on chromosome 1, a region frequently implicated in the progression of several cancers, highlighting CTPS1′s potential involvement in tumorigenesis and making CTPS1 a significant target for cancer research. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, NIH/3T3, K562 cells, using CTPS1 Rabbit Polyclonal Antibody (EAB11069) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human liver carcinoma tissue, using CTPS1 Rabbit Polyclonal Antibody (EAB11069) at 1:100 dilution.
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