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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 48, 49 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CtBP1/2 (Ser158/164) Rabbit Polyclonal Antibody detects endogenous levels of CtBP1/2 protein when phosphorylated at Ser158/164. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CtBP(C-terminal binding protein) plays a crucial role as a transcriptional corepressor, influencing various cellular processes by modulating gene expression. CtBP is involved in the regulation of the p21 promoter in response to DNA damage, a critical function that helps maintain genomic stability. The interaction between CtBP and CtIP, a protein that recognizes distinct motifs, is essential for this regulatory mechanism, as CtIP binds to the BRCT repeats of the breast cancer gene BRCA1, thereby enabling CtBP to influence BRCA1 activity. The ability of CtBP to form complexes with other proteins, such as δEF1, further underscores its significance in transcriptional silencing during skeletal and T-cell development. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells treated with LPS, using Phospho-CtBP1/2 (Ser158/164) Rabbit Polyclonal Antibody (EAB14713) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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