| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, ELISA | 40 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CAB39 Mouse Monoclonal antibody detects endogenous levels of CAB39 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CAB39(Calcium binding protein 39) also known as MO25, CGI-66 plays a crucial role in the regulation of the serine/threonine kinase LKB1, which is a key tumor suppressor involved in cellular energy homeostasis and metabolism. The interaction between CAB39 and LKB1 is vital for proper localization and activation of LKB1, as CAB39 facilitates LKB1 translocation from the nucleus to the cytoplasm, thereby enhancing tumor suppressor functions. Dysregulation of this complex can lead to impaired LKB1 activity, contributing to the development of Peutz-Jeghers Syndrome and increasing the risk of various cancers. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Mouse brain cells, using CAB39 Mouse Monoclonal antibody (EAB22527) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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