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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 34 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CYB5R3 Rabbit Polyclonal Antibody detects endogenous levels of CYB5R3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CYB5R3(Cytochrome b5 reductase 3) also known as DIA1 consists of 301 amino acids and is encoded by the human gene CYB5R3. CYB5R3 plays a crucial role in the desaturation and elongation of fatty acids, cholesterol biosynthesis, and drug metabolism, making CYB5R3 essential for maintaining cellular lipid homeostasis and detoxifying harmful substances. Additionally, in erythrocytes, CYB5R3 is vital for the reduction of methemoglobin, which is important for ensuring efficient oxygen transport in the blood. Notably, a serine residue at position 117 of CYB5R3 is predominantly found in individuals of African descent, highlighting the potential for genetic variation in enzyme function and its implications for health. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, HepG2, HT29, K562 cells, using CYB5R3 Rabbit Polyclonal Antibody (EAB11070) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human placenta tissue, using CYB5R3 Rabbit Polyclonal Antibody (EAB11070) at 1:100 dilution.
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