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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 30 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PLP1 Rabbit Polyclonal Antibody detects endogenous levels of PLP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PLP1(Proteolipid protein 1) is a transmembrane proteolipid protein that is the predominant component of myelin. PLP1 plays a crucial role in the formation and maintenance of myelin sheaths in the central nervous system, which are essential for proper conduction of electrical impulses along nerve fibers. PLP1 is predominantly located in oligodendrocytes, where PLP1 contributes to the structural integrity of myelin, accounting for approximately half of the protein content in adult central nervous system myelin. Mutations in the gene encoding PLP1 are associated with Pelizaeus-Merzbacher disease (PMD), a severe neurological disorder that affects myelination in the brain and leads to significant developmental challenges. |
| Product Image Gallery | |
 Western blot analysis of extracts on U2OS cells, using PLP1 Rabbit Polyclonal Antibody (EAB11083) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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