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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IHC-P, FC, ELISA | 45 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LAMP2 Mouse Monoclonal Antibody detects endogenous levels of LAMP2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LAMP2(Lysosomal associated membrane protein 2) also known as CD107b is a member of a family of membrane glycoproteins. LAMP2 plays a critical role in maintaining lysosomal integrity and acidity, protecting the lysosomal membrane from autodigestion, and facilitating autophagy by mediating the fusion of autophagosomes with lysosomes. LAMP2 is synthesized in the endoplasmic reticulum, sorted at the trans-Golgi network, and trafficked to lysosomes via a pathway distinct from clathrin-coated vesicles. LAMP2 localization to the lysosome is essential for function in cellular homeostasis and the degradation of macromolecules. Dysregulation of LAMP2 expression or function is associated with lysosomal storage disorders, such as Danon disease, and altered expression has been implicated in cancer progression and metastasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, C6, NIH/3T3 cells, using LAMP2 Mouse Monoclonal Antibody (EAB21257) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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