www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 169 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NCAPD3 Rabbit Polyclonal Antibody detects endogenous levels of NCAPD3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NCAPD3 also known as hCAP-D3, KIAA0056 is a crucial component of the condensin-2 complex, which plays a vital role in the organization and segregation of chromosomes during cell division. This 1498 amino acid nuclear protein is characterized by the presence of four HEAT repeats, which are important for protein-protein interactions and structural stability within the complex. The proper functioning of hCAP-D3 is essential for maintaining genomic integrity, as anti-hCAP-D3 antibody (283.7) facilitates the resolution of sister chromatids and ensures accurate chromosome segregation during mitosis. Dysregulation or mutations in hCAP-D3 can lead to chromosomal instability, which is a hallmark of various cancers. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat cells, using NCAPD3 Rabbit Polyclonal Antibody (EAB11640) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
