www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 50 | Human, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | NFS1 Rabbit Polyclonal Antibody detects endogenous levels of NFS1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
NFS1 also known as nitrogen fixation 1 is a crucial enzyme that plays a significant role in the biosynthesis of iron-sulfur (Fe-S) clusters, which are vital cofactors for numerous biological processes. NFS1 is primarily located in the cytoplasm and mitochondria, with localization being influenced by cytosolic pH levels. This dual localization allows NFS1 to participate in various metabolic pathways, including the synthesis of Fe-S clusters that are essential for electron transfer in oxidative phosphorylation and enzymatic reactions in key metabolic enzymes such as aconitase and dehydratases. NFS1′s ability to supply inorganic sulfur for Fe-S cluster assembly underscores its importance in maintaining cellular function and integrity, particularly in energy metabolism and DNA repair mechanisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using NFS1 Rabbit Polyclonal Antibody (EAB11095) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
