WAVE2 Rabbit Polyclonal Antibody
Catalog #:EAB11234
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 54 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity WAVE2 Rabbit Polyclonal Antibody detects endogenous levels of WAVE2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q9Y6W5

Entrez Gene ID

10163

Product Description

WAVE2 also known as WASF2, SCAR2 is a member of the Wiskott-Aldrich syndrome protein family. WAVE2 plays a crucial role in actin cytoskeleton dynamics, particularly in the regulation of membrane ruffling and the formation of actin filament clusters in response to GTP binding. WAVE2 is essential for cellular processes such as migration, shape change, and signal transduction, as WAVE2 interacts with the Arp2/3 complex to promote actin polymerization. WAVE2 is predominantly expressed in peripheral blood leukocytes, highlighting WAVE2′s importance in immune responses and cell motility. WAVE2′s ability to form multiprotein complexes that link receptor kinases with actin underscores WAVE2′s role in translating extracellular signals into cellular responses, making WAVE2 a vital component in understanding cellular behavior in various physiological and pathological contexts.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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