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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 55 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | WAVE3 Rabbit Polyclonal Antibody detects endogenous levels of WAVE3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
WAVE3 also known as SCAR3, WASF3 is a member of the Wiskott-Aldrich syndrome protein family. WASF3 plays a crucial role in actin cytoskeletal dynamics, which is essential for various cellular processes, including cell motility, shape changes, and signal transduction. This interaction is vital for processes such as cell migration and morphogenesis, making WAVE3 a significant player in both normal physiological functions and pathological conditions, including cancer metastasis. The WAVE family, including WAVE1 and WAVE2, cooperates with the Arp2/3 complex to promote actin filament formation, thereby influencing cellular architecture and behavior. WAVE3 mediates actin polymerization in response to GTP binding and activation of Rac, underscoring its importance in maintaining cellular integrity and facilitating dynamic responses to environmental cues. |
| Product Image Gallery | |
 Western blot analysis of extracts on SKBR3, NIH/3T3 cells, using WAVE3 Rabbit Polyclonal Antibody (EAB14416) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using WAVE3 Rabbit Polyclonal Antibody (EAB14416) at 1:100 dilution.
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