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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, FC, ELISA | 22 | Human, Mouse, Monkey |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 FC=1:50-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ASF1B Mouse Monoclonal antibody detects endogenous levels of ASF1B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. ASF1B plays a crucial role in gene expression regulation by acting as a histone chaperone, facilitating nucleosome assembly and disassembly, which is essential for DNA replication and repair. This function ensures proper chromatin remodeling, allowing DNA access for transcription and other cellular processes. ASF1B gene is located on chromosome 19p13.12, and ASF1B interaction with core histones H3 and H4 is vital for maintaining chromatin structure and function. ASF1B also cooperates with CAF1 protein in nucleosome formation, highlighting ASF1B significance in epigenetic regulation of gene expression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, COS7, HCT116 cells, using ASF1B Mouse Monoclonal antibody (EAB22509) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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