| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 74 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BRD7 Rabbit Polyclonal Antibody detects endogenous levels of BRD7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Brd7(Bromodomain containing protein 7) also known as BP75, NAG4, CELTIX1 is a member of the bromodomain-containing protein family. Brd7 plays an important role in cell cycle progression, signal-dependent gene expression and cell growth. Brd7 functions as a tumor suppressor, as is suggested by its apparent suppressive role on nasopharyngeal carcinoma (NPC) cell growth when overexpressed. Specifically, BRD7 negatively regulates the expression of cell cycle related proteins such as cyclin D1 and E2F-3, thereby inhibiting the G1-S progression. Brd7 also interacts with the centrosome associated protein BLOS2 and this BRD7-BLOS2 interaction inhibits the transcriptional suppression activity of BRD7 on various target genes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using BRD7 Rabbit Polyclonal Antibody (EAB11134) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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