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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, FC, ELISA | 85 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Ezh1 Mouse Monoclonal antibody detects endogenous levels of Ezh1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Ezh1 also known as KMT6B, ENX-2 is a component of a noncanonical Polycomb repressive complex-2 (PRC2). Ezh1 plays a crucial role in chromatin regulation and is characterized by the presence of a SET domain, which is essential for histone methylation function. This post-translational modification influences gene expression by altering chromatin structure, thereby impacting cellular processes such as differentiation and development. Ezh1 is expressed ubiquitously in both adult and fetal tissues, suggesting importance in maintaining heterochromatin stability, which is critical for genomic integrity. Human Ezh1 is located on chromosome 17q21, and expression patterns indicate a significant role in the central and peripheral nervous systems, as well as in fetal hematopoiesis during development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using Ezh1 Mouse Monoclonal antibody (EAB22505) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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