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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, FC, ELISA | 26 | Human, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GSTM1 Mouse Monoclonal Antibody detects endogenous levels of GSTM1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GSTM1 plays a crucial role in the detoxification of harmful compounds, as part of the glutathione S-transferase (GST) family, which is essential for cellular defense against toxicants and oxidative stress. Specifically, GSTM1 is involved in conjugating glutathione to a wide range of electrophilic substrates, including carcinogens and environmental toxins, thereby facilitating their excretion and reducing cellular damage. The importance of GSTM1 extends beyond detoxification; variations in GSTM1 expression can influence individual susceptibility to diseases, including cancer, making GSTM1 a significant focus of research in pharmacogenomics and toxicology. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, Jurkat, HepG2, COS7 cells, using GSTM1 Mouse Monoclonal Antibody (EAB22675) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissue, using GSTM1 Mouse Monoclonal Antibody (EAB22675) at 1:200 dilution.
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