LDHC Rabbit Polyclonal Antibody
Catalog #:EAB11186
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 36 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity LDHC Rabbit Polyclonal Antibody detects endogenous levels of LDHC protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P07864

Entrez Gene ID

3948

Product Description

LDHC(Lactate dehydrogenase C) plays a crucial role in cellular metabolism by catalyzing the conversion of L-lactate and NAD to pyruvate and NADH, marking the final step of anaerobic glycolysis. Notably, LDHC is uniquely expressed in testis and sperm, distinguishing LDHC from LDHA and LDHB, which are predominantly found in muscle and heart tissues, respectively. This specific localization underscores LDHC′s importance in male fertility and germ cell tumor diagnostics, making LDH-C a powerful biomarker in reproductive health studies. The genes encoding human LDHA and LDHC are located on chromosome 11, while human LDHB gene is situated on chromosome 12, with deficiencies in LDHA gene being associated with exertional myoglobinuria.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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