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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 19 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | UFC1 Rabbit Polyclonal Antibody detects endogenous levels of UFC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
UFC1 is an E2-like conjugating enzyme for UFM1 (ubiquitin-fold modifier 1) conjugation system that drives ufmylation of protein substrates. This pathway coordinates proteostasis at the endoplasmic reticulum, ER stress signaling, and quality control processes linked to secretory pathway function, with reported roles in ribosome-associated quality control and cellular homeostasis. Disruption of ufmylation components, including UFC1, has been associated with neurodevelopmental phenotypes, hematopoietic defects, and cancer-related cellular stress adaptation in experimental models, supporting its relevance to disease biology. UFC1 is therefore frequently studied in contexts where ER function, stress resilience, and proteome maintenance influence cell fate decisions. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T cells, using UFC1 Rabbit Polyclonal Antibody (EAB11184) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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