| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 41 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MAGE-C2 Rabbit Polyclonal Antibody detects endogenous levels of MAGE-C2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MAGE-C2 also known as CT10 is related to members of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. MAGE-C2 a cancer-testis antigen with restricted expression in normal germline tissues and frequent re-expression in diverse tumors. MAGE-C2 participates in protein homeostasis by engaging ubiquitin-dependent processes, including modulation of E3 ligase activity through interactions with RING-domain partners, thereby influencing stability of signaling and cell-cycle regulators. Dysregulated MAGE-C2 expression has been linked to altered proliferation, stress responses, and transcriptional programs associated with malignant progression and immune recognition. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, SH-SY5Y, 293T, Mouse brain cells, using MAGE-C2 Rabbit Polyclonal Antibody (EAB11210) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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