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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 17 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TSSC3 Rabbit Polyclonal Antibody detects endogenous levels of TSSC3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PHLDA2 also known as TSSC3 is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. PHLDA2 plays a crucial role in regulating fetal and placental growth, making PHLDA2 essential for normal human development. This cytoplasmic protein is predominantly expressed in the placenta and adult prostate, with lower levels found in the liver, lung, and brain. PHLDA2 functions as an apoptosis-related protein and acts as a negative growth regulator, which is vital for maintaining cellular homeostasis during development. Notably, PHLDA2 is imprinted on the placenta, liver, and fetal tissues during embryogenesis, and PHLDA2 expression is tightly regulated, being removed once development is complete. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, HepG2 cells, using PHLDA2 Rabbit Polyclonal Antibody (EAB22694) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue, using PHLDA2 Rabbit Polyclonal Antibody (EAB22694) at 1:100 dilution.
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