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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 52 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | UBA3 Rabbit Polyclonal Antibody detects endogenous levels of UBA3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
UBA3 also known as UBE1C is a 463 amino acid protein that plays a crucial role in the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis. UBA3 is primarily located in the cytoplasm and nucleus, where UBA3 activates NEDD8, a ubiquitin-like protein, thereby regulating vital cellular processes such as cell division, signaling pathways, and embryogenesis. UBA3 functioning is critical, as dysregulation can lead to various diseases, including cancer, due to the accumulation of improperly folded or damaged proteins. UBA3 exists in two isoforms resulting from alternative splicing, which may contribute to functional diversity and regulatory mechanisms within different cellular contexts. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using UBA3 Rabbit Polyclonal Antibody (EAB11253) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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